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Albert J. Sinusas, MDChief of Nuclear Cardiology Specialty: Nuclear Medicine/Nuclear Cardiology
Clinical Interests: Nuclear Cardiology/Cardiac MR/3D echocardiography. Post-infarction remodeling. Research Interests: My research is directed at development of noninvasive imaging approaches for the assessment of myocardial viability, angiogenesis, and post-infarction remodeling. I have been employing the 3-D modalities of single photon emission computed tomography (SPECT), echocardiography and magnetic resonance (MR) imaging for assessment of regional myocardial perfusion, function and metabolism, in an animal physiology laboratory, employing large and small animal models of myocardial infarction, "hibernation", and "stunning". My laboratory is currently focused on targeted molecular imaging, developing non-invasive nuclear imaging strategies for identifying the hypoxic stimulus for angiogenesis, and targeted imaging of selected integrins previously established to modulate the angiogenic process, and evaluation of the role of matrix metalloproteinases on post-infarction remodeling. The investigation of these biological processes involves, in vitro cellular and whole heart preparations, as well as ex vivo and in vivo imaging in both small and large animal models, using dedicated high-resolution and real-time 3D ultrasound imaging system, a hybrid microSPECT-CT imaging system, and large animal SPECT. Board Certifications: Nuclear Cardiology Education: MD, University of Vermont, College of Medicine Residency: Medicine - University of Oklahoma , Health Science Ctr. Fellowship: Cardiology - University of Virginia , Health Science Ctr. Internships: Medicine - University of Oklahoma , Health Science Ctr. Honors / Awards: Best Doctors in America 2001-2002
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