Research

Clinical Research, Division of Clinical Radiology

Funded Clinical Research—Recent or Pending

Robert Fulbright: MR Spectroscopy of Reading Disability and of the Effects of Estrogen on Reading Systems (NIH), High Dimensional Index Imaging in Medical Image Databases (NIH), Randomized Indomethacin GMH/IVH Prevention Trial (NIH), Adolescent Literacy: Classification, Mechanisms, Outcome (NIH), Neuroimaging of Genetically defined Incipient CJD (NIH), Effects of Aging on Memory for Source of Information (NIH/NIA), Risk and Predictors of Intractable Epilepsy in Children: A long-term follow-up (NINDS)

Robin Goodman: Metabolic markers and predictors of childhood obesity (NIH)

Regina Hooley: Clinical trial on Breast Elastography, funded by SuperSonicImagine.

Albert Sinusas: A Pilot Study: Non-invasive Diagnostic Imaging for the Assessment of Vasculopathy and Coronary Artery Disease post Heart Transplantation. Multi-detector Computed Tomography Coronary Angiography, Rubidium-82 Positron Emission Tomography vs. Biplane Coronary Angiography with Intracoronary Ultrasound (Departmental); LV Strain Quantification from 4D Echocardiography (NIH); Measurement of Matrix Metalloproteinase Activation Post Myocardial Infarction (Investigator-Initiated); Detecting heart disease using first pass imaging with gated SPECT perfusion (CDL Medical Tech - pending); Study of Myocardial Perfusion and Coronary Anatomy imaging roles in CAD (SPARC) (Bracco, Astella, GE Healthcare, Siemens and Brigham and Women's Hospital, Partners Healthcare System); A Phase II Study of 99mTc-glucarate in Chest Pain Patients Suspected with ACS with No Obvious Signs of AMI and with Known Previous CAD
(Molecular Targeting Technologies, Inc. (NIH); A Phase I Open Label Pilot Study to Evaluate the Safety, Efficacy and Tolerability of Anginera for Adults With Left Ventricular Dysfunction AND Reversible Myocardial Ischemia undergoing CABG surgery (Theregen, Inc); Validation of the Gated Blood Pool SPECT: Comparison to ERNA and 3-dimensional echocardiography (Departmental).

Jeffrey Weinreb: Phase II sequence optimization of MS325 (gadofosveset) (Epix)
Multicenter Study of In Vivo MR Spectroscopy for the Evaluation of Prostate Cancer; (NCI/ACRIN)